Biotin Supplements Caused Misleading Examination Results, Near Led To Unnecessary Physical Care For
Saturday, July 1, 2017
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Influenza A virus subtype H5N1 novel representative study inward the Journal of the Endocrine Society documents how a patient's purpose of a mutual biotin supplement, also known every bit vitamin B7, caused her to convey clinically misleading examination results, which prompted numerous consultations in addition to unnecessary radiographic in addition to laboratory testing.
The patient inward the representative study took a 5000 mcg dose of biotin daily. Biotin supplements inward that dosage are normally sold over-the-counter, without a prescription, inward many grocery in addition to drug stores for close $8-$20 a bottle. They are marketed every bit beingness skilful for well for y'all hair, peel in addition to nails, but at that topographic point is no scientific prove to back upward this claim.
In this patient's case, "The negative clinical acquit on included weeks of psychological distress concerning the possibilities of hypercortisolemia or a testosterone-producing tumor. Most significantly, these abnormal examination results nearly resulted inward an unnecessary invasive physical care for for a complex patient amongst a hypercoagulable state," the representative study says. Hypercortisolemia is a status involving a prolonged excess of cortisol -- a steroid hormone -- inward blood.
Maya Styner, MD, associate professor of endocrinology in addition to metabolism inward the division of medicine, is the representative report's corresponding author.
"The literature is lacking amongst visit to biotin interference amongst serum cortisol in addition to testosterone immunoassays, every bit inward our case-report," Styner said. "Patients are ingesting supplements inward a higher frequency, in addition to higher doses, in addition to hence this representative is timely in addition to relevant from both a clinical in addition to basic-science perspective."
She added, "Our manuscript is a production of a collaboration betwixt endocrinology, reproductive endocrinology/gynecology in addition to clinical chemical scientific discipline at UNC in addition to at the Mayo Clinic. This collaboration enabled us to ascertain the underlying diagnosis in addition to perform relevant research-based biotin quantification inward our patient's sample."
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