Nutrients From Food, Non Supplements, Linked To Lower Risks Of Death, Cancer

Adequate intake of for sure nutrients is associated amongst a reduction inward all-cause mortality when the nutrient root is foods, simply non supplements, according to a novel study. There was no association betwixt dietary supplement utilization as well as a lower jeopardy of death.

In addition, excess calcium intake was linked to an increased jeopardy of cancer death, which the researchers constitute was associated amongst supplemental doses of calcium exceeding 1,000 mg/day. The study was published on Apr 9 inward Annals of Internal Medicine.
"As potential benefits as well as harms of supplement utilization piece of job on to live on studied, around studies possess got constitute associations betwixt excess nutrient intake as well as adverse outcomes, including increased jeopardy of for sure cancers," said Fang Fang Zhang, M.D., Ph.D., associate professor at the Friedman School of Nutrition Science as well as Policy at Tufts University as well as senior as well as corresponding writer on the study. "It is of import to empathise the purpose that the nutrient as well as its root powerfulness play inward wellness outcomes, especially if the consequence powerfulness non live on beneficial."
The study used a nationally illustration sample comprising information from to a greater extent than than 27,000 the U.S.A. adults ages xx as well as older to evaluate the association betwixt dietary supplement utilization as well as decease from all causes, cardiovascular affliction (CVD), as well as cancer. The researchers assessed whether adequate or excess nutrient intake was associated amongst decease as well as whether intake from nutrient versus supplement sources had whatsoever consequence on the associations.
For the association betwixt nutrient intake as well as the jeopardy of death, the researchers found:

• Adequate intakes of vitamin K as well as magnesium were associated amongst a lower jeopardy of death;
• Adequate intakes of vitamin A, vitamin K, as well as zinc were associated amongst a lower jeopardy of decease from CVD; and
• Excess intake of calcium was associated amongst higher jeopardy of decease from cancer.

When sources of nutrient intake (food vs. supplement) were evaluated, the researchers found:

• The lower jeopardy of decease associated amongst adequate nutrient intakes of vitamin K as well as magnesium was express to nutrients from foods, non from supplements;
• The lower jeopardy of decease from CVD associated amongst adequate intakes of vitamin A, vitamin K, as well as zinc was express to nutrients from foods, non from supplements; and
• Calcium intake from supplement totals of at to the lowest degree 1,000 mg/day was associated amongst increased jeopardy of decease from cancer simply at that topographic point was no association for calcium intake from foods.

In addition, the researchers constitute that dietary supplements had no consequence on the jeopardy of decease inward individuals amongst depression nutrient intake. Instead, the squad constitute indications that utilization of vitamin D supplements past times individuals amongst no sign of vitamin D deficiency may live on associated amongst an increased jeopardy of decease from all causes including cancer. Further interrogation on this potential connectedness is needed.
"Our results back upwards the see that, piece supplement utilization contributes to an increased marking of full nutrient intake, at that topographic point are beneficial associations amongst nutrients from foods that aren't seen amongst supplements," said Zhang. "This study too confirms the importance of identifying the nutrient root when evaluating mortality outcomes."
The study used 24-hour diet cry back information from 6 two-year cycles of the National Health as well as Nutrition Examination Survey, through 2010. For each nutrient, the daily supplement dose was calculated past times combining the frequency amongst the production information for ingredient, total of component per serving, as well as component unit. Dietary intake of nutrients from foods was assessed using 24-hour dietary recalls. Mortality outcomes were obtained for each player through linkage to the National Death Index through Dec 31, 2011, using a probabilistic match.
The authors complaint around limitations, including the duration of dietary supplement utilization studied. In addition, prevalence as well as dosage of dietary supplement utilization was self-reported as well as and thus is dependent acre to cry back bias. Residual confounding may play a purpose inward the observed associations.
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