Which Hurting Medication Is Safest For Arthritis Patients?

In a recent Alimentary Pharmacology & Therapeutics study, arthritis patients taking nonsteroidal anti-inflammatory drugs (NSAIDs) for hurting addition a tum acid-reducing medicine called esomeprazole (Nexium) had infrequent gastrointestinal side effects. Co-prescribed amongst esomeprazole, celecoxib (Celebrex) had ameliorate overall gastrointestinal security than ibuprofen (Advil) or naproxen( Aleve). NSAIDs are oft used to process hurting in addition to articulation inflammation inward people amongst arthritis, but they tin forcefulness out drive harm to the intestinal tract including ulcers in addition to haemorrhage from the tum or intestine. 

In this study, 24,000 arthritis patients were treated amongst 1 of 3 NSAIDs--celecoxib, naproxen, or ibuprofen--in improver to esomeprazole. Over an average follow-up of well-nigh two years on treatment, serious alimentary canal problems occurred inward roughly 3 per K patients on celecoxib in addition to roughly seven per K on ibuprofen or naproxen. 

"Another reassuring finding was that patients who also needed to cause got aspirin (for preventing optic attacks in addition to strokes) had alone slightly to a greater extent than gastrointestinal problems than those who took alone the arthritis medications," said atomic number 82 writer Prof. Neville Yeomans, of the University of Melbourne, inward Australia.

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