Blood Pressure Level Patterns Inwards Middle-Age, Older Adults Associated Alongside Dementia Gamble

Patterns of high blood pull per unit of measurement area inward midlife that extend to belatedly life or high blood pull per unit of measurement area inward midlife followed yesteryear depression blood pull per unit of measurement area afterward inward life was associated amongst increased opportunity for dementia compared to having normal blood pressure. This observational study included well-nigh 4,800 participants who had blood pull per unit of measurement area measurements taken over 24 years at 5 visits addition a detailed neurocognitive evaluation during the 5th too a 6th visit, where dementia was assessed. There were 516 novel cases of dementia diagnosed betwixt the 5th too 6th visits. Study authors written report that compared amongst maintaining normal blood pressure, an increased opportunity of dementia was associated amongst hypertension (greater than 140/90 mm Hg or role of antihypertensive medication) inward midlife (age 54 to 63) that was sustained to belatedly life too a blueprint of hypertension inward midlife too depression blood pull per unit of measurement area (less than 90/60 mm Hg) afterward life. Midlife hypertension followed yesteryear late-life depression blood pull per unit of measurement area too was associated amongst increased opportunity of mild cognitive impairment. Limitations of the study include that the findings may own got been biased because of the increased likelihood that participants amongst higher blood pull per unit of measurement area too poorer knowledge during midlife dropped out of the study. Also, study participants were from Washington County, Maryland; Forsyth County, North Carolina; Jackson, Mississippi; too Minneapolis, too then the results may non endure generalizable to other areas.
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